Information content of polyme rase chain reaction for diagnostics, evaluation of course and results of onychomy cosist reatment
Clinical and mycological studies of 49 patients with onychomycosis of various localization have been conducted. The aim of this study was to examine the information content to use polymerase chain reaction, as a method to confirm the diagnosis of onychomycosis in laboratory conditions, and evaluation of course and results of its treatment. It is shown that the use of polymerase chain reaction increases the probability of onychomycosis verification compared to microscopy by 14.3% and allows to identify the causative agent. In 60% of cases the causative agent of onychomycosis is T. rubrum. The possibility to use the polymerase chain reaction when evaluating the effectiveness of onychomycosis treatment has been established.