Assessment haemostatic effect of designed method endoscopic reparatory-hemostatic injecting ther apygastrointe stinal bleeding
The aim of study was to estimate an efficiency of hemostasis on local transplantation of platelet-rich plasma during reparatory-hemostatic injecting therapy experiment. The proposed method has been applied in experiments on 5 rabbits of both sexes weighing 3-5 kg. After modeling bleeding from anterior wall of the stomach was performed a standard injecting therapy by physiological saline. After modeling bleeding from posterior wall of the stomach injecting hemostatic therapy was complemented by local administration of platelet-rich plasma. The results were evaluated at 1, 7, 14 days. The data analysis shows the effectiveness of proposed links hemostatic techniques. Dynamics of laboratory parameters and blood oxygen saturation level indicates the absence of rebleeding and stability of hemostasis (p<0,05, t - Student's criterion). The proposed method allows to achieve stable and reliable hemostatic effect in of gastrointestinal bleeding model.