Gender dimorphism of serum sulfur-containing aminoacids levels in rats

Abstract

The paper shows that sex is a determining factor of serum sulfur amino acids levels. It was established that serum homocysteine and cysteine in females is significantly lower than in males. Castration of females causes a significant increase of serum sulfur amino acids, whereas testectomy goes with opposite changes. Hormone replacement therapy with estradiol/testosterone approximates serum H2S homocysteine and cysteine to levels in animals without changes of hormonal status.