Results of scanning electron microscopy of human embryos chorionic villi during early pregnancy miscarriage
Abstract
Chorionic villi (CV) is one of the main components of the hematoplacental barrier in the first trimester of fetal development. In our previous studies, we found a possible connection between violations of the hydrocarbon complexes of the CV structural components and the development of sporadic and recurrent pregnancy miscarriages. In other words, in case of structural and functional disorders of the CV their barrier and transport function are violated, which can lead to fading or slow down the development of the fetus. Many researchers studied the structural features of chorionic villi using scanning electron microscopy in the first trimester in normal cases and during pathology, but we were not able to find data on conducting similar studies on early CV, obtained after the sporadic and recurrent pregnancy miscarriage.
The number of syncytial sprouts and the number of microvilli on the surface of the syncytial layer indicate the activity of proliferative processes, excretion and the fullness of the receptor surface of the histological structures of the chorionic villi. The obtained results confirm our previous studies of inferiority of CV during recurrent and sporadic pregnancy miscarriage, including their surface structures (microvilli), and the reduction of proliferative processes and the violation of the receptor component of their structures.
References
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