Premorbid background of bronchial asthma development and function of external respiration in children
Abstract
The article deals with the pathogenetic and etiological features of the development of concomitant allergic and non-allergic pathology in 316 children with bronchial asthma. Among the 253 patients with persistent asthma, there were various allergic manifestations. Predominant allergens dominated among other non-infectious factors and accounted for 40.93% (p<0.05) and prevailed in boys (28.82%; p<0.05) only in the age group of 6 to 7 years. The results of studies of etiological factors that exacerbated intermittent asthma revealed predominance of household allergens in the group of patients 8-12 (16.98%) and 13 to 16 years (20.76%; p<0.05). Spirometric studies of the function of external respiration showed a decrease in the relative values of FEV, OFV, FEV1, PEF and Tiffen's index and relative to the indices of practically healthy children (p<0.05).
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