Features of the course of necrotic enterocolitis in children born prematurely

  • O.S. Yablon
  • N.P. Rusak
  • O.A. Moravskaya
  • S.O. Rusak
  • K.T. Bertsun
  • D.P. Sergeta
  • N.A. Shovkoplyas
Keywords: necrotizing enterocolitis, children born prematurely.


Based on the study of the peculiarities of the clinical course of necrotizing enterocolitis in 50 extremely preterm babies it was found that the heavier course of necrotizing enterocolitis is associated with lower body weight (1180.55±095.02 g) and a lower gestational period (28.66±0.66 weeks). Risk factors for development are delayed enteral nutrition, longer parenteral nutrition, artificial feeding and a longer enteral pause. In the clinical picture of necrotizing enterocolitis, among the nonspecific symptoms, the symptoms of a «white spot», thrombocytopenia (p<0.01) and bradycardia (p<0.05) were significantly more likely to occur, among abdominal manifestations - absence of peristalsis, contouring of the intestinal loops, moderate edema of the anterior abdominal wall (p<0.01), as well as increase in abdominal volume and bloody stool (p<0.05).


1. Znamenska, T. K., Hodovanets, O. S., & Shemanska, N. P. (2014). Osoblyvosti klinichnoi symptomatyky ta diahnostyky porushen funktsionalnoho stanu kyshechnyka u peredchasno narodzhenykh ditei. Neonatolohiia, khirurhiia ta perynatalna medytsyna, IV, 1 (11), 34-38. [in Ukrainian].
2. Karavaeva, S. A. (2002). Diagnostika i osobennosti klinicheskogo techeniya nekroticheskogo enterokolita u detej. Vestnik hirurgii, 4, 41-46. [in Russian].
3. Karpova, I. Yu., & Parshikov, V. V. (2011). Nekroticheskij enterokolit u novorozhdennyh. Detskaya hirurgiya, 6, 47-49. [in Russian].
4. Rusak, P.S., Laponoh, S.P., Vaisberh Yu.R., Serheiko, I. A., Morenets, L. I., Ryzhuk, V. H., & Rusak, N. P. (2016). Vyznachennia markeriv rozvytku nekrotyzuiuchoho enterokolitu v umovakh perynatalnoho tsentru. Neonatolohiia, khirurhiia ta perynatalna medytsyna, VI, 3 (21), 19-24. [in Ukrainian].
5. Cetinkaya, M., Ӧzkan, H., Kӧksal, N., Akaci, O., & Ӧzgur, T. (2010). The efficacy of serial serum amyloid A measure ments for diagnosis and follow-up of necrotizing enterocolitis in premature infants. Pediatr. Surg. Int., 26, 835-841.
6. Hsueh, W., De Plaen, I. G., Caplan, M. S., Xiao-Wu, G., Xiao-Di, T., & Gonzales-Crussi, F. (2007). Neonetal necrotizing enterocolitis: clinical aspects, xperimental models and pathogenesis. World Journal of Pediatrics, 1.3, 17-29.
7. Maheshwari, A. (2015). Immunologic and hematological abnormalities in necrotizing enterocolitis. Clinics in Perinatology, 41, 169-173.
How to Cite
Yablon, O., Rusak, N., Moravskaya, O., Rusak, S., Bertsun, K., Sergeta, D., & Shovkoplyas, N. (2017). Features of the course of necrotic enterocolitis in children born prematurely. Biomedical and Biosocial Anthropology, (29), 136-140. Retrieved from https://bba-journal.com/index.php/journal/article/view/306