Quality of life in patients with osteoarthrosis of knee joints and aberrant production of melatonin and galectin-3

  • O.V. Humeniuk
Keywords: melatonin, 6-sulfatoxymelatonin, galectin-3, osteoarthrosis, knee joint, SF-36, quality of life.


The study covered the indicators of quality of life in patients with osteoarthrosis of knee joints with aberrant production of melatonin and galectin-3. In patients with OA, the reduction of 6-sulfatexymelatonin urine excretion was associated with a moderate decline in the quality of life indicators at the account of SF-36 psychological health component. Instead, raising the blood galectin-3 concentration in patients with OA was associated with a significant decrease of the physical component and a less pronounced decline of the SF-36 psychological health component. Blood galectin-3 and 6-sulfatexymelatonin excretion levels appeared to have an inverse associative dependence.


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How to Cite
Humeniuk, O. (2017). Quality of life in patients with osteoarthrosis of knee joints and aberrant production of melatonin and galectin-3. Biomedical and Biosocial Anthropology, (29), 140-144. Retrieved from https://bba-journal.com/index.php/journal/article/view/307