Ambulatory hypertensive women blood pressure and circadian regulation time profile depending on a presence of underlying iron-deficient anemia in the course of 6-month therapy with ramipril and valsartan in combination with indapamide


  • V.P. Ivanov
  • S.O. Sulym
Keywords: arterial hypertension, iron-deficient anemia, ramipril, valsartan.

Abstract

One hundred and forty one 54-87 year-old women with Stage II arterial hypertension, with and without underlying iron-deficient anemia were surveyed. Study objective was to study the time profile of outpatient hypertensive women blood pressure and circadian regulation depending on the history and severity of underlying iron-deficient anemia in the course of a 6-month therapy with ramipril and valsartan in combination with indapamide. In contrast to ramipril+indapamide SR combination, the administration of valsartan+indapamide SR regimen was associated with a more favorable effect on the circadian profile of blood pressure in all surveyed groups. This was characterized mostly by an increase in the number of patients without episodes of increased blood pressure around the clock, as well as a decrease in the average number of episodes of elevated blood pressure at night, and episodes of symptomatic arterial hypotension.

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Published
2017-10-27
How to Cite
Ivanov, V., & Sulym, S. (2017). Ambulatory hypertensive women blood pressure and circadian regulation time profile depending on a presence of underlying iron-deficient anemia in the course of 6-month therapy with ramipril and valsartan in combination with indapamide. Biomedical and Biosocial Anthropology, (29), 160-166. Retrieved from https://bba-journal.com/index.php/journal/article/view/311