Comparison of quality of life in postoperative patients with cholecystolithiasis and choledocholithiasis. The difference between open and laparoscopic treatment

  • M. M. Halei Volyn Regional Clinical Hospital, Volyn, Ukraine
  • I. Ya. Dziubanovskyi I. Ya. Horbachevsky Ternopil State Medical University, Ternopil, Ukraine
  • I. P. Marchuk Volyn Regional Clinical Hospital, Volyn, Ukraine
Keywords: gallstone disease, laparoscopy, simultaneous, SF-36 quetionnaire.


Gallstone disease is quite common in the adult population and can quickly cause life-threatening conditions that require extensive surgical treatment. In recent years, the assessment of quality of life is becoming increasingly important in world medicine as an indicator of the general condition of the patient and the effectiveness of treatment and rehabilitation measures. The aim of this work – to collect and calculate indicators of quality of life in postoperative patients with gallstones of gall bladder and common bile duct; to compare data from patients with open and laparoscopic treatment; to determine the advantages of the treatment methods. For rating quality of life 36-Item Short-Form Health Status (SF-36) was used. The statistic was collected using retrospective analysis of worked out data in laparoscopic surgery unit in Volynian regional state hospital during 2016–2019 (191 patients). Patients of group I (113 patients) underwent laparoscopic treatment, patients of group II used open surgical treatment (78 people). Statistical processing was performed using the program “Statistica 6.0” (Statsoft Inc., USA). In group I pain level in first two hours was significantly lower than in group II (6.2 vs 8.4 in 10 point scale), in addition, pain relief became faster reaching low pain level of abdomen in 2.48 days. In group II pain level was higher (8.4 points) and pain relief was reached in 5.11 days. Oral nutrition and verticalisation were renewed in 14.7±3.1 hours in group I, and in 22.9±5,5 hours in group II and 6.1±1,9 hours in group I vs 19.7±3,3 hours in group II. Also, according the results SF-36, quality of life indicators indicate faster recovery in the group of laparoscopic treatment compared to the group with the classic version of the operation. The physical functioning and physical performance of the role differed significantly in favor of laparoscopic treatment throughout the follow-up period. Pain indicators in the first group were satisfactory after 1 month of rehabilitation, while in the second group such indicators were achieved only after 6 months – 91/94/94 vs. 74/89/94. Although psychological well-being differed between 1 and 3 months, in favor of minimally invasive treatment, after 6 months the data were comparable in both groups.


[1] Bar-Or, D., Rael, L. T., Madayag, R. M., Banton, K. L., Tanner, A., Acuna, D. L., … & Mains, C. W. (2019). Stress Hyperglycemia in Critically Ill Patients: Insight Into Possible Molecular Pathways. Frontier Medicine, 6, 54. doi: 10.3389/fmed.2019.00054
[2] Bloom, A. A. (2019). What is the pathogenesis of acute Cholecystitis? Emedicine. Medscape / article – 171886. Retrieved from
[3] Hays, R., Bjorner, J. B., Revicki, D. A., Spritzer, K. L., & Cella, D. (2009). Development of physical and mental health summary scores from the patient-reported outcomes measurement information system (PROMIS) global items. Quality of Life Research, 18(7), 873-880. doi: 10.1007/s11136-009-9496-9
[4] Heuman, D. M. (2019). Gallstones (Cholelithiasis). Medscape / article – 175667. Retrieved from
[5] Hu, J., Feng, X., Valdearcos, M., Lutrin, D., Uchida, Y., Koliwad, S. K., & Maze, M. (2018). Interleukin-6 is both necessary and sufficient to produce perioperative neurocognitive disorder in mice. British Journal of Anaesthesia, 120(3), 537e545. doi: 10.1016/j.bja.2017.11.096
[6] Ivanko, O., & Kalina, R. (2012). Comparative assessment of the quality of life of patients after open and laparoscopic appendectomy. Hospital surgery, 3, 26-29. Retrieved from
[7] Jenkinson, C., Layte, R., Jenkinson, D., Lawrence, K., Petersen, S., Paice, C., & Stradling, J. (1997). A shorter form health survey: can the SF-12 replicate results from the SF-36 in longitudinal studies? Journal of Public Health Medicine, 19(2), 179-186. doi: 10.1093/oxfordjournals.pubmed.a024606
[8] Machado, F. H. F., Castro, F. H. F., Babadopulos, R. F. A. L., Rocha, H. A. L., Rocha, J. L. C., & Moraes, F. M. O. (Feb 14 2019). Ursodeoxycholic acid in the prevention of gallstones in patients subjected to Roux-en-Y gastric bypass1. Acta Cir. Bras., 34(1), e20190010000009. doi: 10.1590/s0102-865020190010000009
[9] Mehta, H. B., Dimou, F., Adhikari, D., Tamirisa, N. P., Sieloff, E., Williams, T. P., … & Riall, T. S. (2016). Comparison of Comorbidity Scores in Predicting Surgical Outcomes. Med. Care, 54(2), 180-187. doi: 10.1097/MLR.0000000000000465
[10] Melloul, E., Hübner, M., Scott, M., Snowden, C., Prentis, J., Dejong, C. H. C., … & Demartines, N. (2016). Guidelines for Perioperative Care for Liver Surgery: Recommendations. World Journal of Surgery, 40(10), 2425-2440. doi: 10.1007/s00268-016-3700-1
[11] Mikolasevic, I., Orlic, L., Poropat, G., Jakopcic, I., Stimac, D., Klanac, A., … & Milic, S. (2017). Nonalcoholic fatty liver and the severity of acute pancreatitis. European Journal of Internal Medicine, 38, 73-8. doi: 10.1016/j.ejim.2016.10.019
[12] Milovanovic, A., Grujicic, D., Bogosavljevic, V., Jokovic, M., Mujovic, N., & Markovic, I. P. (2017). Efficacy of Early Rehabilitation After Surgical Repair of Acute Aneurysmal Subarachnoid Hemorrhage: Outcomes After Verticalization on Days 2-5 Versus Day 12 Post-Bleeding. Turk Neurosurg., 27(6), 867-873. doi: 10.5137/1019-5149.JTN.17711-16.1
[13] Novik, A. A., & Ionova, T. I. (2007). Guide to the study of the quality of life in medicine. Moscow: Olma groups.
[14] Scott, M. J., Baldini, G., Fearon, K.C.H., Feldheiser, A., Feldman, L. S., Gan, T. J., … & Carli, F. (2015). Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 1 - pathophysiological considerations. Acta anesthesiology Scandinavica, 59(10), 1212-1231. doi: 10.1111/aas.12601
[15] Smith, R., Kee, A., & Barrat, S. (2008) Depth of anesthesia with desflu-rane does not influence the endocrine-methabolic response to pelvic surgery. Acta Anaesthesiology Scandinavica, 52(1), 99-105. doi: 10.1111/j.1399-6576.2007.01470.x
[16] Tornqvist, B., Waage, A., Zheng, Z., Ye, W., & Nilsson, M. (2016). Severity of acute cholecystitis and risk of iatrogenic bile duct injury during cholecystectomy, a population-based case-control study. World Journal of Surgery, 40(5), 1060-7. doi: 10.1007/s00268-015-3365-1
[17] Vege, S. S., Ziring, B., Jain, R., & Moayyedi, P. (2015). American Gastroenterological Association institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts. Gastroenterology, 148(4), 819-22; quiz 12-3. doi: 10.1053/j.gastro.2015.01.015
[18] World Health Organization. (1948). WHO Definition of Health. Preamble to the Constitution of the World Health Organization as adopted by the International Health Conference, New York, 19-22 June, 1946; Official Records of the World Health Organization, 2, 100.
[19] Zawn Villines. (2019). How does diabetes affect wound healing? Medical news today. Wound Source.,complications%20in%20diabetes%20wound%20healing
How to Cite
Halei, M. M., Dziubanovskyi, I. Y., & Marchuk, I. P. (2020). Comparison of quality of life in postoperative patients with cholecystolithiasis and choledocholithiasis. The difference between open and laparoscopic treatment. Biomedical and Biosocial Anthropology, (36), 47-51.