Provision of vitamin D and risk of development disfunction of cardiovascular system

Abstract

Vitamin D, known mainly for its role in calcium homeostasis, is now thought to be involved in various physiologic and pathologic processes in the human body. 25-Hydroxyvitamin D levels are the most commonly measured indicator of vitamin D status. Serum 25-hydroxyvitamin D is not only a predictor of bone health but is also an independent predictor of risk for cardiovascular diseases. The mechanism for how vitamin D may improve cardiovascular disease outcomes remains obscure; however, potential hypotheses include the down regulation of the renin-angiotensin-aldosterone system, direct effects on the heart and vasculature or improvement of glycemic control.