Comprehensive assessment of structural and functional changes in healthy rats that consumed as drinking water that of lake Katlabuh
The work is devoted to a comprehensive assessment of functional changes in healthy rats organism who consumed as drinking water that of the lake Katlabuh. The results of physico-chemical and sanitary-chemical investigations of the lake Katlabuh water indicate its compliance with the requirements of Ukrainian state standard (DSTU) 4808: 2007 to the sources of 2-4 class quality. 2 species of cyanobacteria Merismopedia minima and Spirulina laxissima, which cause water bloom have been found. The use of healthy rats as a drinking water that of lake Katlabuh was accompanied by compensatory activation of lipid peroxidation in combination with the weakening of the antioxidant defense system. Pathomorphological changes, e.g. degenerative liver changes, hypoxic changes in brain, signs of compensatory depletion activity in the spleen took place as well. It is suggested that the biological effects identified are a consequence of the action of eeither cyanotoxins or any toxic organomineral complexes. The expediency of expansion and continued research of cyanobacteria in the contexts of their detection in water, the identification of cyanotoxins, the impact of these xenobiotics on the state of warm-blooded animals and humans has been substantuated.