Structural features of the genebrain natriuretic peptide and level of its plasma concent ration in menresidents of podillia region
It was investigated the organization of the gene brain natriuretic peptide (BNP T-381C), the level of its plasma concentration, individual dermatoglyphic finger signs and structural and functional characteristics of the heart in healthy men (n=79) who are residents of Podillia region. Genotyping of the gene BNP was performed using polymerase chain reaction. BNP plasma level was determined by ELISA. It was found that in healthy men inhabitants Podillia region dominated genotype T381C. Carriers of genotypes which have a C allele have a higher level of plasma BNP. Carriers the genotype T381T of the gene BNP in healthy men even within the "normal range" is accompanied by higher rates of blood pressure.