Effect of prednisone on metabolism and vitamin D- exchange in its short prolonged admin istration


  • A. V. Kalashnikov
  • L. I. Apuhovska
  • E. L. Kuziv
  • O. O. Viltsanyuk
Keywords: osteoporosis, prednisolone, metabolism, vitamin D- exchange

Abstract

In experiment on 34 Wistar rats studied the impact of prednisolone metabolism and vitamin D-exchange at its intended rate within 30 days. The introduction of prednisolone resulted in a violation of mineral and D - vitamin metabolism through significant reduction of weight gain in rats, reducing levels of calcium, inorganic phosphorus, alkaline phosphatase, isoenzymes of alkaline phosphatase activity and levels of 250HD3 serum compared to animals in the control group and indicates the need for medical correction of these changes.

Published
2017-03-31
How to Cite
Kalashnikov, A. V., Apuhovska, L. I., Kuziv, E. L., & Viltsanyuk, O. O. (2017). Effect of prednisone on metabolism and vitamin D- exchange in its short prolonged admin istration. Biomedical and Biosocial Anthropology, (25), 16-19. Retrieved from https://bba-journal.com/index.php/journal/article/view/65